1. Describe the contributions of Robert Hooke and Anton van Leeuwenhoek to what would become the science of microbiology.
2. Describe the miasma theory of disease.
3. Explain the doctrine of spontaneous generation and outline the work of Redi,
4. Outline the work of Semmelweis and Snow and tell how their work enhanced our understanding of transmission of disease and how such transmission could be interrupted. Define epidemiology.
5. Define variolation and contrast it with vaccination. Describe the work of Jenner and the viruses he worked with.
6. Describe the work of Pasteur in laying the foundation of the germ theory of disease. Tell how Lister supported the theory.
7. Describe Robert Koch’s significant contributions to the germ theory of disease. List Koch’s postulates and tell how they are applied to discovering the etiological agents of disease.
8. Describe the competition that existed between the laboratories of Pasteur and Koch and the reasons for the competition. Briefly describe the important discoveries about anthrax, cholera and diphtheria that come out of each lab. Define attenuate and antitoxin. Tell about Pasteur’s work with rabies and Koch’s work with tuberculosis.
9. Describe the contributions made to microbiology by Fanny Eilshemius Hess, Elie Metchnikoff, Alexander Flemming, Walter Reed, Mary Montague, Howard Ricketts, Paul Ehrlich and Ernst Abbe.
10. Describe the contributions of Ivanowsky and Beijerinck to the science of virology. Define contagious.
11. Explain what is meant by the Classic Golden Age of Microbiology, when it existed and why it came to an end.
12. Be familiar with the stories of the history of microbiology told in lecture.
13. Briefly describe events and dates that distinguish the Second Golden Age of Microbiology. Tell why the Second Golden Age came to an end.
14. Briefly describe the dates and challenges of the Third Golden Age of Microbiology. How are microbial ecology and evolution helping to “drive” the Third Golden Age?
15. “Enrich” your understanding of Koch’s Postulates by reviewing MicroFocus 5.5 in Chapter 5. Be able to summarize the story of the search for the etiological agent for Legionnaires’ disease. This is a fairly common organism; why was this particular population of people so susceptible?
16. Review the summaries and questions at the end of the chapter.
Visit Visit http://microbiology.jbpub.com/8e/index.cfm and take the quiz that accompanies this chapter. Check out the other learning aids at the web site.